By midday Friday, airlines had canceled more than 2,100 U.S. flights from the storm's approach on Wednesday through Sunday, according to tracking service FlightAware.
The region's two largest airports, in Charlotte and Raleigh-Durham, North Carolina, had more than 200 cancellations on Friday. Raleigh and one in eight at Charlotte.
That's not much compared with last year's Hurricane Harvey, which flooded runways at two major airports and caused airlines to scrub more than 11,000 flights in Houston alone.
The Federal Aviation Administration says Charleston International Airport in South Carolina isn't expected to reopen until Monday night. Wilmington International in North Carolina expects to reopen at noon Saturday.